Researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have uncovered a new aspect of cancer biology that could lead to improved treatments for diffuse large B-cell lymphoma (DLBCL), the most common form of blood cancer.
double-hit and triple-hit lymphomas. high-grade B-cell lymphomas, not otherwise specified (NOS) . The classification of lymphoma types are evolving and changing as our understanding of lymphoma biology and behaviour increases.
Lymphoma Biology: Study of lymphoma development, spread, and treatment strategies in the lymphatic system. Molecular Mechanisms of Lymphoma: Involves genetic mutations, chromosomal translocations, and epigenetic changes leading to cancerous lymphocyte growth.
Learn more about non-hodgkin lymphoma overview, symptoms, treatment and more at Dana-Farber Cancer Institute.Our understanding of the biology of non-Hodgkin lymphoma has greatly improved in recent years, and the classification system is changing to reflect this.
B-cell lymphomas grow in aggregates, closely interacting with specific physical elements and cellular environments. While 2D culture systems have long been the standard in the field, current methodologies aim to better replicate lymphoma biology and its microenvironment in 3D.
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